Different roles of S100P Overexpression in Intrahepatic Cholangiocarcinoma: Carcinogenesis of Perihilar Type and Aggressive Behavior of Peripheral Type.
Aishima S, Fujita N, Mano Y, Kubo Y, Tanaka Y, Taketomi A, Shirabe K, Maehara Y, Oda Y. Am J Surg Pathol. 2011 Apr;35(4):590-8.
S100P is a member of the S100 family of calcium-binding proteins that has previously been shown to be overexpressed in pancreatic ductal adenocarcinoma. This group has studied the expression of S100P in cases of biliary intraepithelial neoplasia (BilIN) and cholangiocarcinoma. S100P is expressed more often in perihilar-type (68%) than in peripheral-type (12%) chCA. S100P+ peripheral chCA had a more aggressive behavior than S100P- tumors in this study.
Aishima S, Fujita N, Mano Y, Kubo Y, Tanaka Y, Taketomi A, Shirabe K, Maehara Y, Oda Y. Am J Surg Pathol. 2011 Apr;35(4):590-8.
S100P is a member of the S100 family of calcium-binding proteins that has previously been shown to be overexpressed in pancreatic ductal adenocarcinoma. This group has studied the expression of S100P in cases of biliary intraepithelial neoplasia (BilIN) and cholangiocarcinoma. S100P is expressed more often in perihilar-type (68%) than in peripheral-type (12%) chCA. S100P+ peripheral chCA had a more aggressive behavior than S100P- tumors in this study.
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